PUERTO CACHICAMO, Colombia-The pandemic closed the only school in this remote hamlet, long a stronghold for Marxist guerrillas. With no internet connection for virtual classes, 16-year-old Danna Montilla told her family she was leaving to find work, but instead authorities say she joined a narco-trafficking rebel group.

Last month, Colombia's military bombarded the group's jungle camp, killing Danna, another underage girl and 10 others. Residents here said her death underscored a grim reality: Armed gangs have found fresh recruits from an ample pool of youths who, like Danna, have been out of school because of the coronavirus pandemic.

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Gov. Kate Brown of Oregon announced the members of the state's newly formed Psilocybin Advisory Board this week. Why does Oregon need an official board to offer advice about the active ingredient in magic mushrooms, you ask? Because Oregon is about to become the first state in the country to try to build a support infrastructure through which psychedelic mushrooms can be woven into everyday life. This framework is different from what we've seen before: not legalization, not medicalization, but therapeutic use, in licensed facilities, under the guidance of professionals trained to guide psychedelic experiences. Whoa.

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Voters in four states last year approved the recreational use of marijuana. That is likely to launch a land rush there for warehouses and retail properties.

Similar measures in other states have sparked heated competition for these types of real estate. Owners have been able to charge as much as three times market rates when selling or renting to businesses involved in the cultivation, distribution, processing or sale of cannabis, according to brokers, landlords and cannabis industry executives.

Landlords can charge this pot premium because properties typically have to meet a range of local restrictions to qualify, such as being a certain distance from churches or schools.

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Regarding Sally Satel's review of "Drug Use For Grown-Ups" by Carl L. Hart, neuroscientist and professor of psychology at Columbia University (Bookshelf, Jan. 14): I'm a 44-year-old male who is 15 years into a 25-year sentence for shooting a man four times in a cocaine deal that went sideways. I've been selling and using drugs since I was 12 years old. All three of my uncles are dead from opiate-related deaths. My childhood best friend overdosed from heroin in 2017. Setting aside the arguments that include freedom of choice and putting a dent in the profits of drug cartels, I attempt to look at drugs in a more nuanced way.

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For decades, nitrous oxide has been widespread at raves and music festivals, used as a quick buzz. The drug doesn't have the death toll of the opiate disaster or the widespread popularity of marijuana, but it's widely sold - legally - all over the country, though its consumption outside medical facilities is illegal in many states.

But the inhalant's use and misuse seems to be on the rise, fueled by the stress and isolation of the coronavirus pandemic. It's also in the spotlight this week after the death of Tony Hsieh at 46, the former chief executive of the online shoe empire Zappos, in a house fire in November.

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In a referendum in November, Oregon became the first state to decriminalize the possession of small amounts of heroin, cocaine, methamphetamine and LSD. The move was inspired by a 2001 law in Portugal that removed incarceration as a penalty for drug possession. To judge by "Drug Use for Grown-Ups," Carl Hart welcomed this news, which came too late for him to mention in his provocative and enlightening book. He opens with the announcement: "I am an unapologetic drug user."

Mr. Hart, a professor of psychology and a neuroscientist at Columbia University, asserts that "recreational drugs can be used safely to enhance many vital human activities." He bases his claim on decades of research on the behavioral and physiological effects of drugs in humans, coupled with his personal use. Thanks to drugs, he says, "I am a happier and better person." He asks that we think about drugs in a more nuanced way, even at a time when opioid abuse is still headline news. Thus his book represents a calculated risk-namely, that by portraying drug use as so potentially rewarding for responsible users, it may inadvertently seduce non-grown-ups into hazardous use.

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MEXICO CITY - On June 17, 1971, President Richard Nixon stood in front of the White House press corps and made his historic declaration of a new type of war. "Public Enemy No. 1 in the United States is drug abuse," he said. "In order to fight and defeat this enemy, it's necessary to wage a new all-out offensive."

It would be a government-wide effort, and rally the United States's power abroad to stem the supply of drugs. Among the countries targeted was Mexico, which was home to abundant marijuana production and had been resistant to aerial crop spraying.

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Next year will mark 50 years since President Richard Nixon declared drugs "public enemy number one," launching a new war on drugs that has pumped hundreds of billions of dollars into law enforcement, led to the incarceration of millions of people - disproportionately Black - and has done nothing to prevent drug overdoses. In spite of the widespread, growing opposition to this failed war, made clear yet again on Election Day, punitive policies and responses to drug use and possession persist. As President-elect Joe Biden and Vice President-elect Kamala Harris prepare to take office, it is abundantly clear that they have a mandate from the electorate to tackle this issue.

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The U.S. election didn't produce a blue wave or a red wave, but some are celebrating a green wave as voters in Arizona, Montana, New Jersey and South Dakota approved the legalization of recreational marijuana. Meanwhile, Oregonians decriminalized the possession of small amounts of harder drugs, including cocaine, heroin and methamphetamines. "Drugs, once thought to be the scourge of a healthy society, are getting public recognition as a part of American life," the New York Times gushed.

In reality, drugs are very much a scourge, particularly in the lives of young children. In 2019 parental substance abuse was listed as a cause for a child's removal to foster care 38% of the time, a share that has risen steadily in the past decade. Experts suggest this is an underestimate and the real number may be up to 80%.

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One of America's greatest mistakes over the last century was the war on drugs, so it's thrilling to see voters in red and blue states alike moving to unwind it.

The most important step is coming in Oregon, where voters easily passed a referendum that will decriminalize possession of even hard drugs like cocaine and heroin, while helping users get treatment for addiction. The idea is to address drug use as a public health crisis more than as a criminal justice issue.

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Oregon became the first state in the nation to decriminalize the possession of all illegal drugs and also legalize the use of psilocybin-the active ingredient in hallucinogenic mushrooms-for mental health treatment, after voters passed a pair of ballot measures this week.

Both are the first of their kind in any U.S. state and represent the next frontier in the relaxation of drug laws beyond marijuana.

With results from 76% of precincts reporting early Wednesday morning, 59% of Oregonians approved Measure 110, the drug decriminalization referendum, and 56% voted for Measure 109 on psilocybin therapy, according to the Associated Press.

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Oregon has an addiction problem. Pockets of rural poverty, chronic homelessness and cities with lots of young people have given the state one of the highest rates of substance abuse in the nation. It is also, because there is so little money allocated to it, one of the toughest places to get treatment.

A proposed solution on the ballot next week would be one of the most radical drug-law overhauls in the nation's history, eliminating criminal penalties entirely for personal use amounts of drugs such as heroin, methamphetamine and cocaine. Tax revenues from drug sales would be channeled toward drug treatment.

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Do you have the heart to safely smoke pot? Maybe not, a growing body of medical reports suggests.

Currently, increased smoking of marijuana in public, even in cities like New York where recreational use remains illegal (though no longer prosecuted), has reinforced a popular belief that this practice is safe, even health-promoting.

"Many people think that they have a free pass to smoke marijuana," Dr. Salomeh Keyhani, professor of medicine at the University of California, San Francisco, told me. "I even heard a suggestion on public radio that tobacco companies should switch to marijuana because then they'd be selling life instead of selling death."

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In July, the Canadian province of British Columbia experienced its fifth straight month with more than 100 overdose deaths - and its third above 170 lives lost.

Globally, the World Health Organization reports approximately 500,000 deaths from drugs, over 70 percent of them tied to opioids. In Canada, from January 2016 through December 2019, more than 15,000 people died from apparent opioid-related causes. In 2019 alone, there were over 21,000 "suspected opioid-related overdoses" across nine provinces and territories, excluding Quebec (for which data wasn't provided). The opioid crisis clearly persists at home and abroad.

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Listen to the police

Let's talk about decriminalizing all drugs

We're having a national conversation about policing and criminal justice. Examining our drug laws is a natural extension of this debate

More than nine years ago, writing about the war on drugs, this editorial board encouraged the government of then-prime minister Stephen Harper to get bolder with decriminalizing cannabis.

"By any reasonably broad metric," we wrote then, the war on drugs "has been an abysmal failure. According to estimates by the UN - by no means a liberal organization when it comes to drug policy - worldwide consumption of opiates rose 34.5 per cent from 1998 to 2008, cocaine by 27 per cent, and cannabis by 8.5 per cent. In achieving that abject failure, tens of thousands of people have been killed."

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"Is Marijuana Fueling a Public-Health Crisis?"

The statistic from your editorial, that "95% of heroin and cocaine users report first using pot," doesn't prove much. Remember, 99% of criminal motorcycle-gang members started by riding bicycles.

David Allan Van Nostrand

Boca Raton, Fla.

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SHINAHOTA, Bolivia-During nearly 14 years as president, Evo Morales pampered the Chapare, the coca leaf-growing jungle region of central Bolivia where he got his start in politics.

Mr. Morales expelled U.S. antidrug agents and promoted the health benefits of the coca leaf, the raw material for cocaine, which is legal and chewed by many indigenous people. His socialist government built a paper mill, an airport, and a 25,000-seat soccer stadium in the region. In turn, the farmers gave Mr. Morales, the head of a federation of coca growers, their fervent support.

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It is difficult to keep track of the fallacies and straw men in your reefer madness rant. Start with the obvious: The federal ban on cannabis makes it impossible for legal, federally regulated e-cigarette makers to develop and market safe THC cartridges for vaping. Consequently, most THC cartridges are dangerous bootleg products sold on the black market. Federal legalization would lead to improved product safety for which manufacturers would be held accountable.

The reason unlicensed dispensaries are flourishing in California relates to the state's exorbitant taxes and burdensome regulations. This isn't the case in Colorado and Washington, where an oversupply of legal cannabis outlets has driven prices down so much that state-based growers turn to California's black market in search of profits.

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A surge in vaping related lung illnesses this year caught the medical community by surprise, with the Centers for Disease Control and Prevention (CDC) reporting more than 2,500 lung illnesses and 54 deaths. Politicians are targeting e-cigarettes, but the CDC reported last week that marijuana is so far the greatest common denominator.

This is another reminder that America is undertaking a risky social experiment by legalizing and especially destigmatizing cannabis, and the potential effects are hard to foresee or control. The same political culture that is in a fury over legal opioids, and is trying to bankrupt drug companies as compensation, seems to have no problem celebrating a drug that may be damaging young brains for a lifetime.

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TULSA, Okla. - The teenager had pink cheeks from the cold and a matter-of-fact tone as she explained why she had started using methamphetamine after becoming homeless last year.

"Having nowhere to sleep, nothing to eat - that's where meth comes into play," said the girl, 17, who asked to be identified by her nickname, Rose. "Those things aren't a problem if you're using."

She stopped two months ago, she said, after smoking so much meth over a 24-hour period that she hallucinated and nearly jumped off a bridge. Deaths associated with meth use are climbing here in Oklahoma and in many other states, an alarming trend for a nation battered by the opioid epidemic, and one that public health officials are struggling to fully explain.

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