Oregon became the first state in the nation to decriminalize the possession of all illegal drugs and also legalize the use of psilocybin-the active ingredient in hallucinogenic mushrooms-for mental health treatment, after voters passed a pair of ballot measures this week.

Both are the first of their kind in any U.S. state and represent the next frontier in the relaxation of drug laws beyond marijuana.

With results from 76% of precincts reporting early Wednesday morning, 59% of Oregonians approved Measure 110, the drug decriminalization referendum, and 56% voted for Measure 109 on psilocybin therapy, according to the Associated Press.

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