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1US MN: U Researchers 'Getting Closer' To Trials Of Vaccine For OpioidSat, 14 Apr 2018
Source:Minneapolis Star-Tribune (MN) Author:Olson, Jeremy Area:Minnesota Lines:Excerpt Added:04/17/2018

Researchers at the University of Minnesota are getting closer to clinical trials of a vaccine for opioid addiction.

Three studies published in the past six months show incremental success, including one in the Journal of Pharmacology and Experimental Therapeutics that demonstrated that a vaccine could prevent oxycodone and heroin opioid molecules from reaching the brain.

"We are getting closer," said Marco Pravetoni, the lead researcher who has been studying a vaccine to treat addiction for 10 years.

A vaccine to confront addiction might sound unusual, but it would work like any vaccine by stimulating the immune system to produce antibodies. Instead of targeting influenza or poliovirus, the antibodies would be coaxed to bind to opioid molecules and prevent them from crossing the bloodstream barrier to the brain.

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2US MN: Minnesota's Marijuana Moment: Why To Legalize, By Someone WhoSat, 17 Feb 2018
Source:Minneapolis Star-Tribune (MN) Author:Scott, Paul John Area:Minnesota Lines:Excerpt Added:02/22/2018

With decriminalization advancing coast to coast, legalized pot appears on its way, and Minnesota will light up the debate this year. Change is overdue.

I don't smoke marijuana. There are secret purchases required, plus the learning of code, dealer etiquette, dosing expertise, exotic strains, the latest artisanal delivery systems, and it all sounds way too complicated.

Also, because it's easy to forget this detail, pot is illegal.

But even if pot were decriminalized tomorrow - a proposal on the table at the State Capitol - the chances of my racing out to score some "Chronicles of Narnia" and then heading home to roll up a fatty are, well, slim. Unlike Bill Clinton, the one time I did blaze up, over 20 years ago, I inhaled quite deeply enough to find the effect unpleasant. Some of us have all the feelings of alienation and existential weirdness you could ask for, thank you very much.

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3US MN: Minnesota State Patrol Making More Large Pot BustsTue, 13 Feb 2018
Source:Minneapolis Star-Tribune (MN) Author:Harlow, Tim Area:Minnesota Lines:Excerpt Added:02/13/2018

Latest stops in northwestern Minnesota show surge of drug traffic into the state.

It seemed like an innocuous driving violation: A woman was motoring through Otter Tail County in northwestern Minnesota with an obstructed license plate. Then the observant state trooper discovered she was sitting on packages of marijuana.

Troopers seized more than 300 pounds of the weed during the stop last Friday, the latest of several large pot busts the State Patrol has made in the past few weeks and a sign that the surge of large quantities of pot and illegal drugs into Minnesota is continuing.

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4US MN: Marijuana Deals Turn Deadly For Many In Minn., Even AsSun, 11 Feb 2018
Source:Minneapolis Star-Tribune (MN) Author:Xiong, Chao Area:Minnesota Lines:Excerpt Added:02/11/2018

There aren't a lot of concrete answers as to why marijuana transactions are deadlier, but there are theories.

The morning Kim Ambers turned 50, her oldest son, Richard Ambers, called to wish her a happy birthday. I love you, he told her.

It was a tradition for the Ambers family members to see one another on birthdays, but Kim Ambers' celebration would have to wait. Richard was working and had a Halloween party afterward. The whole family would go out for breakfast the next day, on Oct. 29, 2016.

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