CBD, a cannabis compound, is in everything from gumdrops to bath bombs.

In Maplewood Mall, holiday shoppers pick up CBD tinctures from an organic hemp farm at the Nothing But Hemp kiosk. Festive gift sets with CBD-infused body lotions, shampoos and soaps are available a few miles away at Minnesota Hempdropz. Spot Spa in Minneapolis has CBD oil massages on its list of services and tries to keep pricey gourmet gumdrops from "aspirational" CBD purveyor Lord Jones on its shelves. The problem? They continually sell out.

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Legalizing marijuana is looming as a next big political showdown at the Minnesota State Capitol.

Fully legalizing marijuana in Minnesota is looming as a next big political showdown at the Capitol, as a growing number of states are ending bans on recreational cannabis.

Gov.-elect Tim Walz, who favors ending marijuana prohibition, will replace Gov. Mark Dayton, who doesn't. A new Democratic House majority will debate proposals to legalize next year and will likely take votes on the issue as soon as 2019 or 2020. And, not one but two legal pot parties -- the Grassroots-Legalize Cannabis Party and Legal Marijuana Now Party -- emerged with 5 percent of the vote in statewide elections, giving them "major party status," which means automatic ballot access and the chance for campaign subsidies.

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The Minnesota Department of Health is adding the degenerative neurological disorder to its cannabis program, which includes cancer pain, epileptic seizures, PTSD and autism. Research is limited, but findings suggest that cannabis inhibits the formation of proteins linked to memory loss and dementia.

Alzheimer's disease will be eligible for treatment with medical marijuana in Minnesota starting next year, becoming the 14th health condition certified by the state since the program began in 2015.

The Minnesota Department of Health announced Monday that it was adding the degenerative neurological disorder to its cannabis program, which already includes cancer pain, epileptic seizures, post-traumatic stress disorder and autism.

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Researchers at the University of Minnesota are getting closer to clinical trials of a vaccine for opioid addiction.

Three studies published in the past six months show incremental success, including one in the Journal of Pharmacology and Experimental Therapeutics that demonstrated that a vaccine could prevent oxycodone and heroin opioid molecules from reaching the brain.

"We are getting closer," said Marco Pravetoni, the lead researcher who has been studying a vaccine to treat addiction for 10 years.

A vaccine to confront addiction might sound unusual, but it would work like any vaccine by stimulating the immune system to produce antibodies. Instead of targeting influenza or poliovirus, the antibodies would be coaxed to bind to opioid molecules and prevent them from crossing the bloodstream barrier to the brain.

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With decriminalization advancing coast to coast, legalized pot appears on its way, and Minnesota will light up the debate this year. Change is overdue.

I don't smoke marijuana. There are secret purchases required, plus the learning of code, dealer etiquette, dosing expertise, exotic strains, the latest artisanal delivery systems, and it all sounds way too complicated.

Also, because it's easy to forget this detail, pot is illegal.

But even if pot were decriminalized tomorrow - a proposal on the table at the State Capitol - the chances of my racing out to score some "Chronicles of Narnia" and then heading home to roll up a fatty are, well, slim. Unlike Bill Clinton, the one time I did blaze up, over 20 years ago, I inhaled quite deeply enough to find the effect unpleasant. Some of us have all the feelings of alienation and existential weirdness you could ask for, thank you very much.

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Latest stops in northwestern Minnesota show surge of drug traffic into the state.

It seemed like an innocuous driving violation: A woman was motoring through Otter Tail County in northwestern Minnesota with an obstructed license plate. Then the observant state trooper discovered she was sitting on packages of marijuana.

Troopers seized more than 300 pounds of the weed during the stop last Friday, the latest of several large pot busts the State Patrol has made in the past few weeks and a sign that the surge of large quantities of pot and illegal drugs into Minnesota is continuing.

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There aren't a lot of concrete answers as to why marijuana transactions are deadlier, but there are theories.

The morning Kim Ambers turned 50, her oldest son, Richard Ambers, called to wish her a happy birthday. I love you, he told her.

It was a tradition for the Ambers family members to see one another on birthdays, but Kim Ambers' celebration would have to wait. Richard was working and had a Halloween party afterward. The whole family would go out for breakfast the next day, on Oct. 29, 2016.

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A sleeper issue has emerged among DFL candidates in the 2018 governor's race: Marijuana.

St. Paul Mayor Chris Coleman, state Reps. Erin Murphy, Tina Liebling and Paul Thissen, and U.S. Rep. Tim Walz all support legalizing marijuana for recreational and not just medical use. Among the major DFL candidates, only State Auditor Rebecca Otto declined to do so.

"When you confront the reality of the cost of criminalization vs. the benefits of legalization, I think the benefits outweigh the costs," said Coleman, whose campaign approached the Star Tribune to discuss the issue.

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