Pubdate: Tue, 14 Dec 1999 Source: Guardian, The (UK) Copyright: Guardian Media Group 1999 Contact: http://www.guardian.co.uk/ Author: Sarah Boseley, Health Correspondent CLINICAL TRIAL OF CANNABIS RECRUITS MS SUFFERERS The first clinical trial of cannabis in relieving the pain and symptoms of multiple sclerosis is to go ahead, following approval and a grant of pounds 950,000 from the medical research council. The three year study will be run by John Zajicek, a consultant neurologist at Derriford hospital in Plymouth, but the 660 MS patients involved will be from all over the country. "We hope the study will provide definite scientific evidence about whether or not taking cannabis is helpful to people with MS," said Dr Zajicek. It will be the first time people with a medical condition will have been prescribed cannabis. Many MS sufferers claim the drug helps relieve some of the symptoms, such as muscle stiffness and spasms, as well as the pain. The patients, ones with significant spasticity in some leg muscles, will be recruited from hospital MS clinics. They will not smoke the drug but swallow a capsule of either extract of cannabis or a constituent called tetrahydrocannabinol, or be given a placebo. Multiple sclerosis is the most common neurological disease affecting young adults in the western world and there are estimated to be about 85,000 with the disease in Britain. Peter Cardy, chief executive of the Multiple Sclerosis Society, said: "For years we have pressed for proper medical research. Thousands of people with MS suffer from the often very painful symptoms of spasticity [spasms]. "It is clearly an unacceptable state of affairs when many people suffering from a serious medical condition feel driven to break the law." The Royal Pharmaceutical Society, which helped develop the protocol for the trial, welcomed the news. - --- MAP posted-by: Derek Rea