Pubdate: Mon, 21 Dec 1998
Source: Independent, The (UK)
Contact:  http://www.independent.co.uk/
Copyright: Independent Newspapers (UK) Ltd.

CANTAB SET TO BUY ANTI-SMOKING DRUG

CANTAB PHARMACEUTICALS, the drug development company, will today
offer hope  to millions of smokers and drug addicts with the $9m
(pounds 5.5m) purchase of  two vaccines against nicotine and cocaine.

Cantab is set to reveal that it is buying the two drugs, currently in
clinical trials in the US, from the American biotechnology firm
ImmunoLogic.

The acquisition will be funded through the issue of around two million
Cantab shares at a slight premium to Friday's closing share price of
202.5p, leaving ImmunoLogic with nearly 6 per cent of the UK group.

The deal will give Cantab, which has a number of other vaccines in its
pipeline, access to two potentially huge markets. Recent research
shows that there are 50 million daily smokers in the US alone, 17
million of whom attempt to quit smoking each year. More than $350m is
spent annually on prescription and over-the-counter drugs by people
trying to give up nicotine in the US.

The cocaine vaccine will target the millions of heavy users of the
drug.  In  the US, more than two million people use cocaine on a
regular basis and 900,000  of them seek treatment each year.

The vaccines are designed to generate antibodies that neutralise the
effects of the two substances. Experts believe they could have an edge
over conventional treatments, which have a high relapse rate.

Cantab has also agreed to pay ImmunoLogic a further $11m if the two
vaccines successfully complete Phase II clinical trials - the
intermediate stage of drugs testing. In return, ImmunoLogic will
transfer $6m in cash to Cantab to  fund the development of the two
compounds until the end of the year 2000.

- ---
Checked-by: Rich O'Grady