Pubdate: Mon, 30 Aug 2010 Source: Calgary Herald (CN AB) Copyright: 2010 Canwest Publishing Inc. Contact: http://www2.canada.com/calgaryherald/letters.html Website: http://www.calgaryherald.com/ Details: http://www.mapinc.org/media/66 Author: Sharon Kirkey, Postmedia News Note: Download the study at http://mapinc.org/url/t4KIh82X Bookmark: http://www.mapinc.org/mmj.htm (Cannabis - Medicinal) POT CAN CUT CHRONIC PAIN WITHOUT A HIGH Briefly inhaling cannabis three times a day eases a kind of chronic pain that affects tens of thousands of Canadians -- without making them high -- Montreal researchers are reporting. The new study, the first clinical trial in the world to allow patients to take marijuana home with them and "self-dose," found that for people with neuropathic pain -- a common and dreaded condition that causes electric, stabbing pain -- smoking cannabis reduced pain, improved mood and helped them sleep. Three potencies (2.5 per cent, six per cent and 9.4 per cent) of THC, marijuana's active ingredient, were tested against a placebo in 21 patients with neuropathic pain, none of whom had responded to standard treatments. Participants inhaled a single dose through a pipe three times daily for five days, followed by a nine-day "washout" period. Patients reported less pain, better sleep and less anxiety when they were smoking the highest concentration of THC, compared with the placebo. It wasn't a massive reduction in pain: The average daily pain intensity was 5.4 with 9.4 per cent THC, versus 6.1 with the placebo. "But the patients that we were recruiting had to be patients that had tried and failed all other conventional treatments," said lead author Dr. Mark Ware, director of clinical research at the McGill University Health Centre. The study appears in the latest issue of the Canadian Medical Association Journal. - --- MAP posted-by: Richard Lake