Pubdate: Tue, 09 Dec 2003
Source: New York Times (NY)
Copyright: 2003 The New York Times Company
Contact:  http://www.nytimes.com/
Details: http://www.mapinc.org/media/298
Author: Reuters

BRITAIN TO BAN ANTIDEPRESSANTS FOR CHILDREN

The UK government is set to ban the prescription of antidepressant drugs for
children because of evidence they can cause them to become suicidal, The
Guardian newspaper reported on Wednesday.

A spokesman for the Department of Health declined to comment on the report
but said the government's watchdog on drug safety -- the Medicines and
Healthcare Products Regulatory Agency (MHRA) -- would be making a statement
later on Wednesday.

The Guardian reported that after looking at details of clinical trials
carried out by drug companies in the 1990s, the MHRA has told doctors not to
prescribe all but one of the antidepressants known as selective serotonin
reuptake inhibitors (SSRIs).

The exception is Prozac, which is licensed for use in depressed children in
the United States.

The MHRA will be advising doctors not to prescribe Cipralex, a
second-generation antidepressant manufactured by Danish group Lundbeck A/S
(LUN.CO), its predecessor drug Cipramil, as well as Lustral, manufactured by
Pfizer Inc (PFE.N) and Faverin.

Earlier this year, the UK authorities said that Wyeth's (WYE.N)
anti-depression drug Effexor should not be taken by children. Effexor is not
licensed for use in people under 18 but it was nevertheless prescribed to an
estimated 3,000 British youngsters. The government also advised in June that
GlaxoSmithKline Plc's (GSK.L) anti-depression drug Seroxat should be not
prescribed to children.
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MAP posted-by: Josh