Pubdate: Thu, 27 Feb 2003
Source: Independent  (UK)
Copyright: 2003 Independent Newspapers (UK) Ltd.
Contact:  http://www.independent.co.uk/
Details: http://www.mapinc.org/media/209
Author: Paul Kelbie

CANNABIS CAN CAUSE 'VANISHING LUNG SYNDROME', SAY DOCTORS

Regular cannabis smoking was blamed yesterday by doctors for causing a rise 
in a debilitating disease known as "vanishing lung syndrome".

Doctors treating respiratory illnesses in people aged 25 to 40 are 
increasingly finding the condition, associated with tobacco smoking, in 
patients who have seldom, if ever, smoked normal cigarettes.

Cannabis smokers are particularly at risk because they hold smoke in their 
lungs for longer than other smokers and marijuana spliffs are rolled 
without filters. Last month, a doctor in Newcastle had to do a lung 
transplant on a patient who had only ever smoked cannabis.

At the Glasgow Royal Infirmary, Dr Mark Johnson, a specialist registrar in 
respiratory medicine, said he had found a regular stream of patients 
showing signs of the syndrome, a form of emphysema that reduces the surface 
of the lungs and replaces it with huge cysts known as giant bullae.

The result was that the alveoli, the air sacs in the lung that permit the 
transfer of oxygen into the blood, are restricted by the cysts and in 
effect collapse the lung.

"Much more work needs to be done in this field," said Dr Johnson yesterday. 
"Every couple of months I finding a new patient showing signs of this 
condition but nobody knows for sure just how many people are affected." 
Research by Dr Johnson and his colleagues found patients who smoked two to 
three spliffs a day suffered similar lung damage to smokers who inhaled 
more than 20 cigarettes a day. The study found cannabis smokers inhaled 
more deeply and held the smoke in their lungs up to four times longer than 
tobacco users.

"When this smoking practice is combined with the lack of filter tips on 
marijuana cigarettes, it leads to a fourfold greater delivery of tar and a 
five times greater increase in carboxyhemoglobin per cigarette smoked," 
they concluded.

"It is a condition that has also been reported in heroin smokers," Dr 
Johnson said. He found sufferers are predominately male, between 25 and 40, 
and chronic cannabis smokers.

Other ill-effects associated with marijuana use included cancer, 
schizophrenia and impotence.
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